Alastin Skincare addresses this directly. Backed by more than 50 peer-reviewed dermatological publications, Alastin is the number one peri-procedural skincare brand in the United States and is now available in the UK at SKINSTATION. Its proprietary TriHex Technology, a patented blend of active peptides and botanicals, is formulated to support the skin's natural ability to clear damaged collagen and elastin proteins while promoting the production of healthy replacements. Each formulation is designed to complement aesthetic procedures and support daily skin restoration.
What Is Peri-Procedural Skincare?
Peri-procedural skincare refers to a targeted skincare protocol used before and after a clinical aesthetic treatment. The term covers the full treatment window: skin preparation in the weeks before a procedure, immediate post-treatment care and the recovery phase that follows.
Standard skincare formulations are not designed for this context. Many everyday actives, including exfoliating acids and high-concentration retinols, are contraindicated during the acute recovery phase following procedures such as laser resurfacing, microneedling, radiofrequency treatments and chemical peels. Skin in recovery requires formulations that support the barrier and the skin's natural repair processes without introducing additional stress.
Peri-procedural skincare addresses three distinct phases:
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Pre-treatment preparation: supporting the skin barrier and collagen and elastin infrastructure ahead of the procedure to improve baseline skin condition.
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Immediate post-treatment recovery: supporting the skin's natural repair response and protecting the barrier during the acute healing window.
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Ongoing maintenance: sustaining skin quality between treatment sessions.
The Alastin range is formulated to support all three phases, with each product validated in pre- and post-procedure contexts.
What Is TriHex Technology?
TriHex Technology is the proprietary active system used across the Alastin range. It is a patented blend of peptides and botanicals formulated to work at the level of the extracellular matrix, the structural layer within the skin responsible for firmness, elasticity and texture. Over time, this matrix accumulates degraded collagen and elastin proteins that no longer contribute to skin structure, a process accelerated by UV exposure and ageing.
Most topical collagen-support products focus on stimulating new protein production. TriHex Technology takes a two-stage approach:
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Stage one: supports the skin's natural clearance of damaged and degraded collagen and elastin proteins, creating space within the extracellular matrix for healthy structural proteins to form.
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Stage two: supports the production of new collagen, elastin and hyaluronic acid (HA) to rebuild the matrix from within.
This mechanism is validated through biopsy-based analysis and gene-expression science, providing direct evidence of structural change at the cellular level. The clinical evidence base spans more than 50 peer-reviewed dermatological publications.
Who Is Alastin Suited To?
Alastin is suited to adults seeking clinically validated skincare support in one or more of the following contexts:
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Those currently undergoing or planning a clinical aesthetic treatment, including laser resurfacing, microneedling, radiofrequency, chemical peels or injectable treatments.
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Those managing visible skin concerns such as fine lines, loss of firmness, uneven tone, post-inflammatory discolouration or dehydration, who want a peptide-based daily restorative protocol.
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Those who have previously undergone aesthetic treatment and want to support long-term skin quality between sessions.
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Sensitivity-prone or post-procedure skin requiring formulations free from potential irritants during recovery.
Key products within the core range are formulated without parabens, dyes and fragrances. The range is pregnancy and breastfeeding safe and validated for use across all skin tones and types. Those with known skin concerns or active clinical conditions are advised to consult their practitioner before use.
Discover The Alastin Range at SKINSTATION
The following products are available at SKINSTATION as part of the Alastin core range. Each is formulated with TriHex Technology and addresses a specific stage of skin restoration or procedure support.
Restorative Skin Complex
A daily treatment formulated to address visible signs of ageing. TriHex Technology supports the skin's production of new collagen and elastin, while L-Ornithine and Hexapeptide-38 can help restore volume to thinning skin and improve elasticity over time. Suited to daily restoration and anti-ageing maintenance.
HA Immerse Serum
A multi-weight hyaluronic acid (HA) serum combined with active peptides. Delivers both immediate surface hydration and supports the skin's own HA production at a cellular level over time. Suited to dehydrated, post-procedure and barrier-compromised skin. Apply beneath moisturiser for additional hydration support.
A-LUMINATE Brightening Serum
A brightening treatment formulated to address pigmentation across multiple stages of formation. Targets post-inflammatory discolouration, uneven tone and surface dullness through a peptide-based approach, without traditional actives such as hydroquinone. Suited to those managing uneven tone or discolouration.
Restorative Eye Complex
A multi-concern eye treatment for the periorbital area, the delicate skin surrounding the eye contour. Contains caffeine, which can help reduce the visible appearance of puffiness, alongside TriHex Technology to support skin quality around the eye. Addresses fine lines, loss of firmness, uneven tone and visible puffiness. Suited to periorbital restoration and post-procedure eye care.
How to Use Alastin: Building a Routine
Daily Maintenance Routine
For those using Alastin as part of a daily skincare programme, the recommended application order is as follows:
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Cleanse with a gentle, non-stripping cleanser.
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Apply Restorative Skin Complex to face and neck, morning and evening.
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Apply HA Immerse Serum beneath moisturiser where additional hydration support is required.
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Apply A-LUMINATE Brightening Serum to areas of visible pigmentation or uneven tone.
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Apply Restorative Eye Complex to the periorbital area.
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In the morning, apply a broad-spectrum SPF. A mineral formulation such as Obagi Sun Shield Mineral SPF 50 is suitable for sensitivity-prone skin.
Peri-Procedural Routine
When using Alastin as part of a clinical treatment protocol, follow specific guidance from your treating practitioner, as application timing may vary depending on the procedure type. The general framework is as follows:
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Pre-treatment (from approximately 4 weeks before): introduce the Restorative Skin Complex and HA Immerse Serum to support baseline skin condition and the extracellular matrix ahead of treatment.
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Immediately post-treatment: begin applying Alastin products as directed by your practitioner. Key formulations are designed for use on compromised skin during the acute recovery phase.
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Recovery phase (weeks 2 to 6): continue the restorative routine to support collagen and elastin regeneration, barrier function and treatment outcomes.
Book a complimentary virtual consultation with the SKINSTATION team for personalised guidance on building a peri-procedural routine with Alastin.
How Alastin Differs From Standard Skincare
Most skincare products address surface-level concerns, targeting hydration, exfoliation, tone and texture through actives that interact with the outermost skin layers. TriHex Technology operates differently. It is formulated to support structural change within the extracellular matrix, the deeper connective tissue layer responsible for skin firmness and elasticity.
Key points of difference include:
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Mechanism: TriHex Technology supports the clearance of damaged proteins before promoting new, well-structured replacements. This two-stage process differs from single-mechanism collagen-stimulators that focus only on new protein production.
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Validation: Clinical evidence is derived from biopsy-based analysis and gene-expression measurement, providing structural data at the cellular level rather than relying on surface assessment or consumer perception surveys alone.
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Procedure compatibility: Alastin formulations are validated for use during the acute post-procedure period, when many standard actives are not appropriate. This makes the range applicable within a clinical treatment programme, not only as a standalone cosmetic routine.
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Formulation: Key products are free from parabens, dyes and fragrances, reflecting the tolerability requirements of post-procedure and sensitivity-prone skin.
